sportiellomike.github.io

I am an MD/PhD student interested in T cell memory and bioinformatics in the lab of Dave Topham at the University of Rochester. Feel free to contact me at sportiellomike@gmail.com for further communication.

Publications

• Sportiello M, Poindexter A, Reilly EC, Geber A, Lambert Emo K, Jones TN, Topham DJ. Mouse Memory CD8 T Cell Subsets Defined by Tissue-Resident Memory Integrin Expression Exhibit Distinct Metabolic Profiles. Immunohorizons. 2023 Oct 1;7(10):652-669. doi: 10.4049/immunohorizons.2300040. PMID: 37855738; PMCID: PMC10615656..
• Reilly EC, Sportiello M, Emo KL, Amitrano AM, Jha R, Kumar ABR, Laniewski NG, Yang H, Kim M, Topham DJ. CD49a Identifies Polyfunctional Memory CD8 T Cell Subsets that Persist in the Lungs After Influenza Infection. Front Immunol. 2021 Sep 9;12:728669. doi: 10.3389/fimmu.2021.728669. PMID: 34566986; PMCID: PMC8462271.. Github repo
• Alon R, Sportiello M, Kozlovski S, Kumar A, Reilly EC, Zarbock A, Garbi N, Topham DJ. Leukocyte trafficking to the lungs and beyond: lessons from influenza for COVID-19. Nat Rev Immunol. 2021 Jan;21(1):49-64. doi: 10.1038/s41577-020-00470-2. Epub 2020 Nov 19. PMID: 33214719; PMCID: PMC7675406.
• Emo K, Reilly EC, Sportiello M, Yang H, Topham DJ. T cell and chemokine receptors differentially control CD8 T cell motility behavior in the infected airways immediately before and after virus clearance in a primary infection. PLoS One. 2020 Aug 20;15(8):e0227157. doi: 10.1371/journal.pone.0227157. PMID: 32817719; PMCID: PMC7444504.
• Topham DJ, Reilly EC, Emo KL, Sportiello M. Formation and Maintenance of Tissue Resident Memory CD8+ T Cells after Viral Infection. Pathogens. 2019 Oct 18;8(4):196. doi: 10.3390/pathogens8040196. PMID: 31635290; PMCID: PMC6963622.